Postdoctoral Fellow in Protein Design

The Department of Molecular Biosciences, Wenner-Gren Institute (MBW) conducts experimental basic research in molecular cell biology, integrative biology and infection and immune biology. The research environment is characterised by a modern and advanced methodology and has a strong international profile. MBW is one of the larger departments of the Faculty of Science at Stockholm University with more than 30 research groups and about 200 employees, of whom about 60 are doctoral students. Read more about MBW at www.su.se/mbw.

Project description

The position will be associated with the laboratory side of protein design. This includes evaluating the characteristics of designed proteins and other biomolecules that interact with proteins. These proteins can e.g. be DNA binding, bind to other proteins or have catalytic capabilities. There will be a strong focus on binding and applying laboratory techniques for evaluating interactions with proteins using techniques such as surface plasmon resonance (SPR) and cell assays. Theoretical knowledge of protein biophysics and modern computational methods is necessary.

Main responsibilities

• Independently evaluate protein interactions using affinity methods such as SPR.
• Design laboratory workflows for efficient analysis of chemical aspects of proteins and other biomolecules.
• Apply machine learning tools for protein design and assess the feasibility of generated designs.
• Large-scale data analysis.
• Expression and purification of designed protein products in various cell systems.

Qualification requirements

Postdoctoral positions are appointed primarily for purposes of research. Applicants are expected to hold a Swedish doctoral degree or an equivalent degree from another country.

Assessment criteria

The degree must have been completed at latest before the employment decision is made, but no more than three years before the closing date. An older degree may be acceptable under special circumstances. Special reasons refer to sick leave, parental leave, elected positions in trade unions, service in the total defense, or other similar circumstances as well as clinical attachment or service/assignments relevant to the subject area.

In the appointment process, special attention will be given to research skills such as: Affinity methods, Cell assays, Protein production and purification, Protein design, Demonstrated ability to work independently and Cell culture.

About the employment

The position involves full-time employment for a minimum of two years and a maximum of three years, with the possibility of extension under special circumstances. Start date 2025-03-01 or as per agreement.

We offer

With us, you will experience the dynamic interaction between higher education and research that makes Stockholm University an exciting and creative environment. You will work in an international environment and get favourable conditions. The university is located in the National City Park with good transport links to the city.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact

Further information about the position can be obtained from Dr. Patrick Bryant, telephone: +49 1512 353 42 91, patrick.bryant@live.com.

Application

Apply for the position at Stockholm University's recruitment system. Attach a personal letter and CV as well as the attachments requested in the application form. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

The instructions for applicants are available at: How to apply for a position.